Coax cable of any length, with RF signal use, effects signal for sure.
What quality/name cable are you using? This is very important.
Cellular RF is a oscillating frequency signal. This run over a cable creates an inductive reactance that acts like a resistor would in a DC circuit. (basically restricts the strength of the out flow). The longer the cable, the higher the resistance.
At 150 foot length you are basically killing a large amount of signal gain from your high powered antenna.
Examples:
You said you had Band 2 connected. Band two is at approximately 1900MHz.
If you have 150' foot of LMR200 equivalent cable and connected band 2, using the Bolton antenna, you are starting with approximately 24dBi of signal gain at the antennas connector. Over the 150' at 1900Mhz on ~LMR200 coax you will be left with about 2dBi (assume you replaced a set of 3 dBi omnis) leaves you with -1dBi of signal gain ignoring connector losses; which shouldn't be too much by its self. Terrible considering the cost of the antenna plus cabling. The only benefit here is that the antenna is up in the air getting a signal from the open air versus trying to pick it up through your walls.
https://www.timesmicrowave.com/Calculat ... uency=1900
If you have 150' foot of LMR400 equivalent cable and connected band 2, using the Bolton antenna, you are starting with approximately 24dBi of signal gain at the antennas connector. Over the 150' at 1900Mhz on ~LMR400 coax you will be left with about 14dBi (assume you replaced a set of 3 dBi omnis) leaves you with 11dBi of signal gain ignoring connector losses; which shouldn't be too much. Worst case you are left with about 8-10dBi of gain. That's no too bad but its not ~$300 +cable costs per antenna good.
https://www.timesmicrowave.com/Calculat ... uency=1900
If you have 150' foot of LMR600 equivalent cable and connected band 2, using the Bolton antenna, you are starting with approximately 24dBi of signal gain at the antennas connector. Over the 150' at 1900Mhz on ~LMR600 coax you will be left with about ~17dBi (assume you replaced a set of 3 dBi omnis) leaves you with ~14dBi of signal gain ignoring connector losses; which shouldn't be too much. Worst case you are left with about ~12-14dBi of gain. That's better but again its not ~$300 +cable costs per antenna good. Especially since LMR600 at 150' would be VERY EXPENSIVE.
https://www.timesmicrowave.com/Calculat ... uency=1900
If you connect to a higher frequency band the [gain] numbers get worse. Connect to a lower band the numbers improve a little.
Also, if you are using only one antenna you are crippling your modem. It works, but it will work MUCH better with a matched pair of antennas. I would go thiw router before placing $300-$800 in a booster system, which might end up with boosted noise and a low quality, though stronger, connection.
Boosters have a place, but they aren't a cornucopia of solution that the marketing for them would have you believe.